[et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n
[\/et_pb_text][et_pb_divider divider_weight=”8px” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Text” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n
“The observation of symptom remission in ADRC-treated patients, illustrated in Emilie’s case, underscores the potential of these cells to profoundly influence physiology in ways that remain mechanistically unclear. As a scientist with extensive experience in epigenetic reprogramming of stem cells, I believe this phenomenon presents a critical opportunity for systematic investigation.<\/em><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Text” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n By unraveling the molecular mechanisms underlying ADRC-driven reprogramming, we could identify biomarkers or genetic conditions that predict treatment success. This understanding could not only enable targeted patient selection for ADRC therapy but also pave the way for broader, innovative applications of this promising cell therapy.”<\/em><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider divider_weight=”8px” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Text” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n “Ambrose Cell Therapy’s approach for treating patients with rare genetic disorders like Emilie’s shows surprising results. The hypothesis that ADRCs could modulate gene expression via epigenetic regulation should be evaluated in rigorous clinical trials.”<\/em><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_divider divider_weight=”8px” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][et_pb_text admin_label=”Text” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n “The remarkable therapeutic effect of autologous ADRC transplantation for diverse rare genetic diseases such as Emilie suggests that – in addition to wound healing and immunomodulatory mechanisms -ADRCs modify pathogenic gene expression in certain patients.<\/em> [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default”][et_pb_column _builder_version=”4.27.4″ _module_preset=”default” type=”4_4″][et_pb_contact_form _builder_version=”4.27.4″ _module_preset=”default” _unique_id=”de8aebda-f7cf-44ad-b8fd-4ec24358bd05″ email=”matt@ambrosecelltherapy.com” hover_enabled=”0″ sticky_enabled=”0″][et_pb_contact_field field_id=”Name” field_title=”Name” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Email” field_title=”Email Address” field_type=”email” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][et_pb_contact_field field_id=”Message” field_title=”Message” field_type=”text” fullwidth_field=”on” _builder_version=”4.16″ global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Scientific Advisory Board Recommendation”The observation of symptom remission in ADRC-treated patients, illustrated in Emilie’s case, underscores the potential of these cells to profoundly influence physiology in ways that remain mechanistically unclear. As a scientist with extensive experience in epigenetic reprogramming of stem cells, I believe this phenomenon presents a critical opportunity for systematic investigation.By unraveling […]<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-9958","page","type-page","status-publish","hentry"],"yoast_head":"\nMary {Cindy) Farach Carson, Ph.D.
Professor Rice University
AMBROSE SCIENTIFIC ADVISORY BOARD<\/h6>\nGianni Soldati Ph.D.
FOUNDER AND PRESIDENT OF THE
SWISS STEM CELL FOUNDATION, CHIEF SCIENCE OFFICER
AMBROSE CHIEF SCIENTIFIC OFFICER<\/h6>\n
An FDA-approved clinical trial that includes advanced cell sample testing before and after ADRC infusion to test the hypothesis that ADRCs induce epigenetic modifications that are responsible -at least in part-for clinical improvement in rare disease patients is called for.”<\/em><\/p>\nBruno Peault Ph.D.
PH.D. PROFESSOR UCLA
AMBROSE SCIENTIFIC ADVISORY BOARD MEMBER<\/h6>\n