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Sam was a productive dentist, recreational golfer, proud parent, and happy husband. However, in 2013 his wife Flo, a retired physician, began a bold twenty-year battle to reverse his dementia, vascular disease, and pre-diabetes. In April 2020, Sam suffered a stroke and contracted Covid and pneumonia in the hospital. He remained there for two months.<\/p>\n
In March 2022, Sam and his wife, Flo, exercised Sam’s Right-to-Try AMBROSE Cell Therapy. Seven months later, he stated, “I am a new man. I have much more energy. My thinking is clearer. I was worried about myself at one time, but not anymore.”<\/p>\n
We will return to Sam\u2019s story in a moment; first, some background on the power of blood flow and the risks of ischemia (lack of blood flow).<\/p>\n
Sam’s Lifeblood \u2013 a) Blood is essential for life Finally, the Greeks believed good and virtuous blood characterized a courageous, valiant, and principled person.[1]<\/a><\/sup><\/p>\n Following the Ancients\u2019 theme, Merriam-Webster defines lifeblood as “the seat of vitality.”\u00a0<\/strong><\/p>\n Ischemia \u2013 Sam’s life suck The Po River nourishes Northern Italy’s expansive farms. But 2022’s global heat wave starved Italy’s breadbasket of vital nutrients and harmed the economy,<\/p>\n Similarly, Sam’s blood flow feeds his cells, tissues, and organs, but inflammation-induced ischemia sucked the vitality from Sam’s life.<\/p>\n In short, Sam’s diffuse (widespread) vascular, metabolic, and musculoskeletal disease foretold of dementia and the stroke yet to come.[3]<\/a><\/sup> [4]<\/a><\/sup><\/p>\n Flo\u2019s Relentless Quest Unfortunately, Sam’s vascular disease caught up with him in early 2020. He had a stroke and contracted Covid and pneumonia in the hospital, requiring a two-month stay. Research has since revealed that the Corona-19 virus attacks the endothelium (inner lining of the blood vessels), adding more risk to Sam’s future. [5]<\/a><\/sup><\/p>\n In 2021, Flo, a retired physician, became concerned that her husband had plateaued. After researching stem cell therapy options, she recommended Ambrose Cell Therapy to Sam in 2022.<\/p>\n Sam\u2019s Disease Progression Cardiologists refer to HTN as the silent killer because it leads to heart attacks and strokes.<\/p>\n From 2009 to 2019, the deaths attributable to high BP rose by two-thirds, an astonishing number considering that one in four adults take antihypertensive medications.[6]<\/a><\/sup> [7]<\/a><\/sup><\/p>\n Flo’s Distrust A British\u00a0study<\/a>\u00a0published in 2004 suggested that Aricept has “disappointingly little overall benefit and is not worth the cost.\u201d<\/p>\n In May 2022, Sam presented to Ambrose with:<\/p>\n Harnessing Sam’s Innate Biology After Sam’s improvement stalled, she took the logical next step of researching stem cell therapy. But Google search results ranked common misinformation high. \u201cAren\u2019t umbilical cord stem cells (UBSCs) more potent and effective than fat stem cells?” she asked.<\/p>\n Our critical review of Tony Robbin’s Life Force<\/a> sets the record straight: Researchers have established that ADRCs are the most accessible, abundant, and potent cell population. Contrary to the extant dogma, stem cell depletion does not apply to ADRCs.[17]<\/a><\/sup><\/p>\n Dozens of peer-reviewed studies<\/a> supported the potential to treat Sam’s combined disabilities in a single outpatient procedure.<\/p>\n Making an informed choice \u00a0<\/strong>Ischemia \u2013 the Tip of the Iceberg A Golden Era of Self-Cell Repair<\/a> details the research and discovery path upon which we base Ambrose Cell Therapy\u2019s safety and potential effectiveness. \u00a0[22]<\/a><\/sup><\/p>\n Sam\u2019s Personalized Protocol Summary of Benefits He helps Flo with chores and preparing dinner and takes the initiative to attend church, meditate, and exercise. He engages in conversation without repeating himself. Flo wants to see his short-term memory improve but acknowledges Sam\u2019s significant quality of life improvement.<\/p>\n Sam\u2019s cholesterol remained high until Flo put him on Zetia and a low dose of Crestor. The keto diet raises cholesterol in some and lowers it in others.<\/p>\n Setbacks He also had a flare of debilitating back pain. Notably, his current MRI shows multi-level spinal degeneration and facet arthritis. However, his months of better function, including long walks and restarting golf, lend credence to the Ambrose Cell-Assisted Spine Care Hypothesis<\/a>.<\/p>\n With rest and conservative physical therapy, Sam said, \u201cMy back is better.\u201d He resumed his daily walks a few weeks later.<\/p>\n Sam\u2019s Perspective \u201cIt\u2019s going well. I am doing very much better. I am playing golf. We are visiting our son and grandchildren in Hamptons this weekend,\u201d declared Sam.<\/p>\n He had quit golf four years ago and had not visited his family in several years.<\/p>\n Details – Sam\u2019s improving quality of life timeline (<\/strong>edited for brevity and clarity):<\/strong><\/p>\n As 2022 came to an end, Flo said, \u201cMatt, I\u2019d like to thank you for your support all year long. It\u2019s been a great year for us.\u201d<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.18.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_divider _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}” admin_label=”Divider”][\/et_pb_divider][et_pb_text _builder_version=”4.27.4″ text_font_size=”80%” text_line_height=”1.5em” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n [1]<\/a><\/sup> John Meletis and Kostas Konstantopoulos The Beliefs, Myths, and Reality Surrounding [2]<\/a><\/sup> https:\/\/www.mocatest.org\/about\/<\/a><\/p>\n [3]<\/a><\/sup> Birdsill AC, Carlsson CM, Willette AA, et al. Low cerebral blood flow is associated with lower memory function in metabolic syndrome. Obesity 2013; 21: 1313\u20131320<\/p>\n [4]<\/a><\/sup> Hoscheidt et al.\u00a0 Insulin resistance is associated with lower arterial blood flow and reduced cortical perfusion in cognitively asymptomatic middle-aged adults Journal of Cerebral Blood Flow & Metabolism 37(6)<\/p>\n [5]<\/a><\/sup> Levy et al. Endothelial Injury in COVID-19 and Acute Infections Arterioscler Thromb Vasc Biol. 2021;41:1774\u20131776<\/em><\/p>\n [6]<\/a> Tsao C et al.\u00a0 Heart Disease and Stroke Statistics\u20142022 Update: A Report From the American Heart Association Circulation Vol 145 Issue 8 February 2022<\/sup><\/p>\n [7]<\/a><\/sup> Satoh M et al. Lifetime Risk of Stroke and Coronary Heart Disease Deaths According to Blood Pressure Level Hypertension AHA Volume\u00a073,\u00a0Issue\u00a01,\u00a0January 2019;\u00a0Pages\u00a052-59<\/p>\n [8]<\/a><\/sup> Patwa J, Flora SJS. Heavy Metal-Induced Cerebral Small Vessel Disease: Insights into Molecular Mechanisms and Possible Reversal Strategies.\u00a0International Journal of Molecular Sciences<\/em>. 2020; 21(11):3862.<\/p>\n [9]<\/a><\/sup> Siblerud, Robert et al. \u201cA Hypothesis and Evidence That Mercury May be an Etiological Factor in Alzheimer’s Disease.\u201d\u00a0International journal of environmental research and public health<\/em>\u00a0vol. 16,24 5152. 17 Dec. 2019,<\/p>\n [10]<\/a><\/sup> Genchi, Giuseppe et al. \u201cMercury Exposure and Heart Diseases.\u201d\u00a0International journal of environmental research and public health<\/em>\u00a0vol. 14,1 74. 12 Jan. 2017<\/p>\n [11]<\/a><\/sup> Houston, M.C. (2011), Role of Mercury Toxicity in Hypertension, Cardiovascular Disease, and Stroke. The Journal of Clinical Hypertension, 13: 621-627.<\/p>\n [12]<\/a><\/sup> Garfield et al.\u00a0\u00a0HbA1c and brain health across the entire glycaemic spectrum.\u00a0Diabetes Obes Metab<\/em>.\u00a0\u00a02021;\u00a023:\u00a01140\u2013\u00a01149.<\/p>\n [13]<\/a><\/sup> Cummings, J,\u00a0Lee, G,\u00a0Nahed, P, et\u00a0al.\u00a0\u00a0Alzheimer’s disease drug development pipeline: 2022.\u00a0Alzheimer’s Dement<\/em>.\u00a0\u00a02022;\u00a08:e12295<\/p>\n [14]<\/a><\/sup> Cummings, JL,\u00a0Goldman, DP,\u00a0Simmons-Stern, NR,\u00a0Ponton, E.\u00a0\u00a0The costs of developing treatments for Alzheimer’s disease: A retrospective exploration.\u00a0Alzheimer’s Dement<\/em>.\u00a0\u00a02022;\u00a018:\u00a0469\u2013\u00a0477.<\/p>\n [15]<\/a><\/sup> The scale and profile of global dementia research funding https:\/\/alzimpact.org\/research<\/a><\/p>\n [16]<\/a><\/sup> Park, Hae-Young et al. \u201cThe Association between Polypharmacy and Dementia: A Nested Case-Control Study Based on a 12-Year Longitudinal Cohort Database in South Korea.\u201d\u00a0PloS one<\/em>\u00a0vol. 12,1 e0169463. 5 Jan. 2017<\/p>\n [17]<\/a><\/sup> Willerson J and Perin E Buying New Soul J Am Coll Cardiol. 2012;60(21):2250-2251<\/p>\n [18]<\/a><\/sup> Morris ME et al. Systemically Delivered Adipose Stromal Vascular Fraction Cells Disseminate to Peripheral Artery Walls and Reduce Vasomotor Tone Through a CD11b+Cell-Dependent Mechanism STEM CELLS TRANSLATIONAL MEDICINE <\/em>2015;4:369\u2013380<\/p>\n [19]<\/a><\/sup> Shigematsu, Kazuo, et al. “Repeated intravenous infusion of autologous adipose\u2010derived stem cells improves cognitive function.”\u00a0Alzheimer’s & Dementia<\/em>\u00a017 (2021): e049907.<\/p>\n [20]<\/a><\/sup> Ohta et al. Autologous adipose mesenchymal stem cell administration in arteriosclerosis and potential for anti-aging application: a retrospective cohort study Stem Cell Research & Therapy (2020) 11:538<\/p>\n
<\/strong>Ancient Eastern societies (Phoenicians, Persians, Egyptians, and Hebrews) attached beliefs about blood to the origins of religion. Some Greek savants considered blood the same as the soul or spirit.<\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Life-Blood-Vitality-450x600.jpg\")
Further, the Greeks developed the first scientific considerations about blood. Back in Homer’s time (8th<\/sup> or 9th<\/sup> Century BC), they summarized four concepts that remain valid to day:<\/p>\n
b) Death is considered final when a lack of blood causes it
c) Clashes in which murder and blood make their appearance are horrible
d) Tribes, nations, and families regard blood as a bond<\/p>\n
<\/strong>![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Ischemia-600x450.jpg\")
In 1885, Rudolph Virchow coined “ischemia” to characterize the lack of blood flow in an organ or tissue. In plain words, ischemia means blood is not moving through your capillaries, blood vessels, veins, or arteries.<\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Depressed-Asian-561x600.jpg\")
Sam’s long decline<\/strong><\/p>\n\n
![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Sam-eating-tuna-with-a-cigarette-600x450.jpg\")
Sam’s history epitomizes the complexity of age-related ill health:<\/p>\n\n
<\/strong>In 2016, Flo found Dr. Dale Bredesen and the RECODE protocol. For several years Sam responded to RECODE. His MoCA score improved from 16 to 19.<\/p>\n
<\/strong>Sam\u2019s first sign of ischemia was elevated blood pressure or hypertension (HTN). “His BP became a problem at least ten years ago.\u201d, recalled Flo.<\/p>\n\n
<\/strong>Flo, a retired physician, lacked confidence in the standard-of-care drugs, e.g., Donepezil (Aricept) and Memantine (Namenda). “I didn’t let the doctors put Sam on those medications. I saw they had short-term benefits but could make things worse with long-term use.”<\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Doctor-Writing-7-Rxs-with-7-Bottles-600x420.jpg\")
Flo also knew to steer clear of drug combinations, including anti-depressants, anti-psychotics, anti-seizure, and sleep meds (polypharmacy). Neurologists prescribe polypharmacy to patients with neurodegenerative diseases despite its well-documented contribution to the progression and severity of dementia. In other words, drug companies profit, and patients pay the price. [13]<\/a><\/sup> [14]<\/a><\/sup> [15]<\/a><\/sup> [16]<\/a><\/sup><\/p>\n\n
<\/strong>![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Buying-New-Soul-Paper-577x600.jpg\")
Flo believed in the body’s power to heal itself. That is why she was attracted to the RECODE protocol.<\/p>\n
<\/strong>![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Article-Image-600x417.jpg\")
Flo requested papers supporting potential benefits for Sam’s memory.<\/p>\n\n
<\/strong>A robust body of literature confirms that ischemia is just the tip of the dementia iceberg. As we have discussed in articles on cell-assisted brain care<\/a>, aging<\/a>, and long-Covid recovery<\/a>, chronic disease involves multisystem dysregulation.<\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Sams-Multisystem-Dysregulaiton-1024x236.jpg\")
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Per the Ambrose Master Protocol<\/a>:<\/p>\n\n
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<\/strong>Per Flo, over ten months, Sam went from reclusive, demented, and in chronic back pain to socializing with friends, playing an occasional round of golf, and enjoying his grandchildren.<\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Boston-Heart-Report-600x443.jpg\")
Consistent with the studies Ambrose provided to Flo, objective evidence indicates cell therapy lowered Sam\u2019s risk of another catastrophic stroke or a heart attack.<\/p>\n\n
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<\/strong>To be clear, Sam has had a few setbacks, including a bout of severe constipation. Diet changes resolved that issue.<\/p>\n
<\/strong>\u201cStem cells are the future. I am a new man. I have much more energy. I am thinking much more clearly. I was worried about myself at one time, but not anymore.\u201d<\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2023\/01\/Improved-Symptom-Quality-of-Life-1024x265.jpg\")
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the Word Hema (Blood) from Homer to the Present Anemia Volume 2010, Article ID 857657<\/p>\n
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