The complex nature of the immune system includes a wide variety of responses and triggers that sometimes turn against one\u2019s own body, resulting in autoimmune disorders. Today, an estimated 50 million Americans live with conditions involving an inflammatory immune response, and women are disproportionately affected.[1]<\/a><\/sup><\/p>\n Inflammation can be triggered by trauma, infection, environmental toxins, lifestyle choices (e.g., smoking), hereditary factors or a combination of those bad actors. The cells in the immune system are there to guard the body, fight infections and other disease processes, and to assist healing. When they sense the enemy, they send out defensive troops of pro-inflammatory molecules. This immediate type of inflammation is essential for repairing the body and fighting infection. It is usually local and short-lived, disappearing once the healing process has taken place.<\/p>\n Inflammation is only problematic when it lingers, becoming chronic, and affects the entire body, becoming systemic. Chronic, systemic inflammation is the hallmark of autoimmune disease.[2]<\/a><\/sup>\u00a0In AI, the immune response is hijacked. The normal orderly, limited immune process goes out of control, into a damaging inflammatory-immune response. This starts a vicious cycle that promotes chronic and systemic inflammation.<\/p>\n The inflammatory-immune response is tantamount to having a backseat driver who is chronically overreacting while \u2018helping\u2019 you drive. It leads to reduced blood flow. Without good circulation, cells die off and scars form; eventually, tissues and then organs degenerate. AI diseases can destroy joints, intestines, connective tissue, internal organs, nerves and brain cells. We call this the Spiral of Degeneration.<\/p>\n Autoimmune diseases involve a chronic systemic inflammatory-immune response perpetuating the Spiral. This can progress to involve the lungs, heart, kidneys, brain and liver, and even predispose to cancer. Many patients have two or more autoimmune conditions concurrently.<\/p>\n Ones\u2019 own fat (adipose tissue) is a rich storehouse of stem and regenerative cells. In the early research days, stem cells were thought to only have the function of regenerating healthy tissue and nerves. But it is now known that adipose-derived stem and regenerative cells\u00a0 (ADRCs) promote tissue repair in many ways.<\/p>\n Through a mechanism of cell-to cell communication, ADRCs work to mobilize nearby cells to work more efficiently. ADRCs assemble an extended team by recruiting additional \u2018repairmen\u2019 at the site of disease or injury, stimulating local stem cells to get back on the job and do their part to decrease inflammation and quiet down the overactive immune responses. Once the backseat driving diminishes, the stem and regenerative cells continue their work by increasing circulation with new blood vessel growth, preventing further cell death, and decreasing scar size. Finally stem cells become the building blocks for the regeneration of healthy tissue and nerves.[3]<\/a>[4]<\/a>[5]<\/a><\/sup><\/p>\n In addition to modulating the inflammatory immune response in AI, the healing process can extend to include repair actions in organs affected by autoimmune diseases. New blood vessels can form and new neurons in the brain can be generated as a result of the multiple activities the ADRCs perform. There can be regeneration of the myelin sheathing that insulates the nerves, of connective tissue that supports muscle and bone, and the cartilage in joints.[7]<\/a><\/sup><\/p>\n <\/p>\n Adipose-Derived Stem and Regenerative Cells (ADRCs) have the potential to help patients living with autoimmune diseases to improve symptoms, function and quality of life. ADRCs are a diverse population of cells that have multiple actions to bring about healing and repair. Scientists researching adult stem cell therapy for autoimmune diseases now widely recognize that ADRCs reduce inflammation and rebalance the immune system in initiating the process of repair.[8]<\/a><\/sup> These cells are akin to having your own, personalized biologic repair crew. Waiting quietly for a sign of trouble\u2014inflammation\u2014they migrate to the damaged sites to do their jobs.[9]<\/a><\/sup><\/p>\n AMBROSE Cell Therapy represents a minimally invasive option for patients with autoimmune diseases. Please contact us for more information about treatment, candidacy and how to become a patient.<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.17.6″ text_font_size=”14px” text_line_height=”1.6em” custom_padding=”0px|||||” global_module=”7842″ global_colors_info=”{}”][\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font=”||||||||” text_font_size=”80%” text_line_height=”1.5em” global_colors_info=”{}”]<\/p>\n [1]<\/a> Ortona E, Pierdominici M, Maselli A, Veroni C, Aloisi F, Shoenfeld Y. Sex-based differences in autoimmune diseases. Ann Ist Super Sanita. 2016 Apr-Jun;52(2):205-12.<\/p>\n [2]<\/a> Pohl D, Benseler S. Systemic inflammatory and autoimmune disorders. Handb Clin Neurol. 2013;112:1243-52.<\/p>\n [3]<\/a> Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 2001;7(2):211\u201328.<\/p>\n [4]<\/a> Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell. 2002;13(12):4279\u201395.<\/p>\n [5]<\/a> Nakagami H, Maeda K, Morishita R, Iguchi S, Nishikawa T, Takami Y, Kikuchi Y, Saito Y, Tamai K, Ogihara T, Kaneda Y. Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol. 2005;25(12):2542\u20137.<\/p>\n [6]<\/a> Qi K, Li N, Zhang Z, Melino G. Tissue regeneration: The crosstalk between mesenchymal stem cells and immune response. Cell Immunol. 2018 Apr;326:86-93.<\/p>\n [7]<\/a> Gimble JM, Katz AJ, Bunnell BA. Adipose-Derived Stem Cells for Regenerative Medicine. Circ Res. 2007 May 11; 100(9): 1249\u20131260.<\/p>\n [8]<\/a> Volarevic V, Gazdic M, Simovic Markovic B, Jovicic N, Djonov V, Arsenijevic N. Mesenchymal stem cell-derived factors: Immuno-modulatory effects and therapeutic potential. Biofactors. 2017 Sep 10;43(5):633-644.<\/p>\n [9]<\/a> Eggenhofer E, Luk F, Dahlke MH, Hoogduijn MJ. The life and fate of mesenchymal stem cells. Front Immunol. May 2014, Volume 5, Article 148:1-6.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Footer CTA” _builder_version=”4.15.1″ _module_preset=”6ea0bfdb-1736-47ec-a731-c9b3bd89f568″ global_module=”317″ saved_tabs=”all” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” background_blend=”multiply” width=”50%” max_width=”80%” custom_padding=”|||” animation_style=”slide” animation_direction=”top” animation_intensity_slide=”3%” use_custom_width=”on” width_unit=”off” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_text_color=”#FFFFFF” header_text_color=”#FFFFFF” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ parallax=”on” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_button button_url=”https:\/\/ambrosecelltherapy.com\/contact\/” button_text=”Learn More” button_alignment=”center” _builder_version=”4.16″ _module_preset=”default” background_layout=”dark” custom_margin=”30px||||false|false” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Since the 1970s, the use of stem cells to treat autoimmune (AI) disease has been an area of intense research. Today, using patients\u2019 own stem cells, new treatment opportunities have been made possible outside of the research setting. AMBROSE Cell Therapy brings patients a safe therapeutic approach beyond immunosuppressant drugs \u2013 drugs that can have […]<\/p>\n","protected":false},"author":9,"featured_media":8028,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":" [mk_page_section layout_structure=\"half_right\" bg_image=\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2018\/11\/shutterstock_537411319.jpg\" bg_color=\"#1aa7aa\" min_height=\"500\" js_vertical_centered=\"true\" padding_top=\"0\" padding_bottom=\"0\"][vc_column][mk_fancy_title color=\"#ffffff\" size=\"37\" force_font_size=\"true\" size_phone=\"20\" font_weight=\"400\" txt_transform=\"capitalize\" letter_spacing=\"1\" margin_bottom=\"30\" font_family=\"none\"]OUR BREAKTHROUGH IN STEM CELL THERAPY[\/mk_fancy_title][vc_column_text disable_pattern=\"false\" css=\".vc_custom_1541183975816{margin-bottom: 0px !important;}\"]We are leading the frontier to the innovation and discoveries. We are the first and only center in the US treating patients with our unique Ambrose Cell Thereapy.<\/span>[\/vc_column_text][\/vc_column][\/mk_page_section][vc_row][vc_column][mk_padding_divider size=\"80\"][\/vc_column][\/vc_row][vc_row][vc_column width=\"1\/6\"][\/vc_column][vc_column width=\"2\/3\"][mk_fancy_title color=\"#353535\" size=\"28\" force_font_size=\"true\" size_tablet=\"20\" size_phone=\"26\" font_weight=\"400\" txt_transform=\"capitalize\" letter_spacing=\"1\" font_family=\"none\" align=\"center\"]what exactly is Ambrose Cell Therapy?[\/mk_fancy_title][vc_column_text align=\"center\" css=\".vc_custom_1541189399372{margin-bottom: 0px !important;}\"]Adult stem cell therapy is the process of isolating the stem and regenerative cells found in patients\u2019 own body fat and re-introducing them into damaged zones of the body and\/or systemically to address underlying factors of chronic, degenerative disease. Through minimally invasive adult stem cell therapy, \u00a0the body\u2019s own natural healing capabilities are put to work for each patient.<\/p> To understand what stem cells are capable of first requires an understanding of a concept known as The Cycle of Disease. Although not all chronic disease is created equal with the same components, many share common denominators such as early inflammation, immune response, loss of blood supply, premature cell\/tissue death and resultant scarring.<\/p> The treatment protocols of Okyanos are based on a thorough understanding of the multiple factors involved in each of the disease processes we treat. Stem cells have the unique advantage that they are able to address multiple aspects of the Cycle of Disease in a single treatment. Adult stem cells could be thought of as small physicians in the way that they go to work healing and repairing the body on a daily basis. Stem cells exist throughout our bodies and are responsible for healing our bumps and bruises and helping us recover from every day wear-and-tear.<\/p> Restorative adult stem cells can be separated from your fat tissue and delivered to specific areas of the body in need of special attention. Because they have the capacity to detect issues\u00a0in the body which are causing pain or dysfunction, stem cells are able to respond and provide the correct \u201ctools\u201d needed for healing.[\/vc_column_text][mk_divider style=\"shadow_line\" margin_top=\"30\" margin_bottom=\"70\"][\/vc_column][vc_column width=\"1\/6\"][\/vc_column][\/vc_row][vc_row][vc_column width=\"1\/6\"][\/vc_column][vc_column width=\"2\/3\"][mk_fancy_title color=\"#353535\" size=\"28\" force_font_size=\"true\" size_tablet=\"20\" size_phone=\"26\" font_weight=\"400\" txt_transform=\"capitalize\" letter_spacing=\"1\" font_family=\"none\" align=\"center\"]What sets Ambrose apart from other cell therapies?[\/mk_fancy_title][vc_column_text align=\"center\" css=\".vc_custom_1541185650115{margin-bottom: 0px !important;}\"]<\/p> Our state-of-the-art facility is located in a government-regulated environment with routine oversight from regulators to ensure safety, and includes a Class C operating theater and Philips bi-plane cath lab for treating patients with cardiovascular disease and issues. Their team of doctors and medical staff include world-class physicians from each medical specialty including cardiology, orthopedics and neurology. These factors combine to make Ambrose a truly world-class cell therapy experience unlike anywhere else in the world that we are aware.<\/p> [\/vc_column_text][\/vc_column][vc_column width=\"1\/6\"][\/vc_column][\/vc_row][vc_row][vc_column][mk_padding_divider][\/vc_column][\/vc_row][mk_page_section bg_color=\"#f8f8f8\" bg_repeat=\"no-repeat\" bg_stretch=\"true\" js_vertical_centered=\"true\" padding_top=\"60\" padding_bottom=\"60\" sidebar=\"sidebar-1\"][vc_column width=\"1\/6\"][\/vc_column][vc_column width=\"2\/3\"][mk_fancy_title color=\"#353535\" size=\"28\" force_font_size=\"true\" size_tablet=\"20\" size_phone=\"26\" font_weight=\"400\" txt_transform=\"capitalize\" letter_spacing=\"1\" margin_top=\"20\" font_family=\"none\" align=\"center\"]Frequently Asked Questions[\/mk_fancy_title][vc_accordions][vc_accordion_tab icon=\"mk-moon-user-8\" title=\"Who is a candidate for stem cell therapy?\"][vc_column_text align=\"center\" css=\".vc_custom_1541185911237{margin-bottom: 0px !important;}\"]<\/p> Determining if a patient is a good candidate for treatment is a highly individualized process for each patient at Okyanos. The medical team will review each individual\u2019s medical records to determine whether cell therapy is appropriate for the condition at hand.<\/p> Requirements:<\/strong><\/p> [\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab icon=\"mk-icon-clock-o\" title=\"How long does stem cell therapy take?\"][\/vc_accordion_tab][vc_accordion_tab icon=\"mk-moon-stats-up\" title=\"What are the potential benefits for patients with chronic conditions?\"][vc_column_text align=\"center\" css=\".vc_custom_1541184868898{margin-bottom: 0px !important;}\"]<\/p> The stem and regenerative cells stored in your body fat could be likened to small \u201cphysicians\u201d who diagnose and correct individual areas of the body in need of special attention. Because these cells have the capacity to detect changes in the body which are causing pain or dysfunction, they respond and communicate with the body\u2019s needs to provide the correct tools needed for healing. These adult stem cells are commonly referred to as \u201crepair cells,\u201d their primary functions being:<\/p> Re-introducing your own stem cells into an injured area of the body\u2014be it a joint, damaged heart or other tissue\u2014can stimulate new blood flow in these areas while reducing inflammation. Cell therapy enables the stem cells in your body to do their job as tiny little \u201cphysicians\u201d in the process of healing. Learn more about the potential benefits of cell therapy for chronic conditions\u00a0here<\/a>.<\/p> [\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab icon=\"mk-icon-exclamation-circle\" title=\"What are the risks?\"][vc_column_text align=\"center\" css=\".vc_custom_1541184924750{margin-bottom: 0px !important;}\"]<\/p> The risks are minimal. Okyanos therapies have been shown to be safe and efficacious in scientific and\/or medical literature for the conditions we treat, and there have been zero reports of cell-related adverse effects\u00a0 using a patient\u2019s own adipose-derived stem and regenerative cells (ADRCs). Further, because these cells are autologous (a patient\u2019s own) the risk of cell rejection is eliminated. For cardiac patients, the risk of bleeding is very low and the procedure is similar to having an angioplasty.<\/p> [\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab icon=\"mk-icon-question-circle\" title=\"Why adispose (fat) stem cells, not bone marrow?\"][vc_column_text align=\"center\" css=\".vc_custom_1541184924750{margin-bottom: 0px !important;}\"]<\/p> The risks are minimal. Okyanos therapies have been shown to be safe and efficacious in scientific and\/or medical literature for the conditions we treat, and there have been zero reports of cell-related adverse effects\u00a0 using a patient\u2019s own adipose-derived stem and regenerative cells (ADRCs). Further, because these cells are autologous (a patient\u2019s own) the risk of cell rejection is eliminated. For cardiac patients, the risk of bleeding is very low and the procedure is similar to having an angioplasty.<\/p> [\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab icon=\"mk-icon-money\" title=\"Do you offer financing?\"][vc_column_text align=\"center\" css=\".vc_custom_1541185517582{margin-bottom: 0px !important;}\"]<\/p> We ask that you call and provide us with information about your specific condition so that we may advise you on pricing. Although cost is an important factor, it isn\u2019t the only factor. Allow us to learn about you so we can determine if our treatment is right for you.<\/p> We can refer you to several financing sources that may work for you. Please visit our\u00a0Financing page<\/a>\u00a0to learn more.<\/p> [\/vc_column_text][\/vc_accordion_tab][vc_accordion_tab icon=\"mk-icon-money\" title=\"Do you offer financing?\"][vc_column_text align=\"center\" css=\".vc_custom_1541185517582{margin-bottom: 0px !important;}\"]<\/p> We ask that you call and provide us with information about your specific condition so that we may advise you on pricing. Although cost is an important factor, it isn\u2019t the only factor. Allow us to learn about you so we can determine if our treatment is right for you.<\/p>Inflammatory-Immune Response<\/strong><\/h3>\n
![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2018\/12\/Inflammatory-Immune-Response-600x230.jpg\")
<\/a><\/p>\n![\"Spiral](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2019\/04\/Spiral-of-Degeneration-600x467.png\")
<\/a><\/p>\nStem Cell Repair<\/strong><\/h3>\n
![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2020\/08\/Cell-to-Cell-Slide-600x207.jpg\")
These actions describe how the body naturally heals – sometimes it just needs reinforcements. We call this the Process of Repair, as it involves the multiple mechanisms of action that are needed to bring the systemic inflammation and immune system back to balance.[6]<\/a><\/sup><\/p>\n![\"\"](\"https:\/\/ambrosecelltherapy.com\/wp-content\/uploads\/2021\/10\/Process-of-Repair-600x259.jpg\")
<\/p>\nAMBROSE Cell Therapy for Autoimmune Diseases<\/strong><\/h3>\n
AMBROSE Cell Therapy<\/h1>\n
Your Right to Try<\/span><\/h3>\n