3 yo – Developmental Disabilities – 6 weeks progress

Hannah, 3-yo, was born with dysgenesis (thinning) of the corpus callosum (DCC). The CC is the band of nerves between the brain’s left and right hemispheres. DCC causes developmental disabilities. The attending pediatrician rated Hannah’s gross motor skills at 8-mo*.

Per Mom, baseline symptoms included non-verbal, limited eye contact, not sleeping through the night, and staring at her left hand.

We curated the literature, consulted three cell therapy KOLs who confirmed mechanisms of potential effectiveness of an ADRC-based treatment. Along with a literature review, the attending physician also established safety of using Mom’s ADRCs with a pediatric oncologist.

On Feb 15, 2022, Hannah received ~50 million of her Mother’s ADRCs through IV. Mom is keeping a daily journal. Improvements include:

  • First audible words, “mommy, mommy, mommy, mommy”
  • Excellent eye contact
  • Sleeping through the night
  • Exceptional improvement in walking. No longer stroller dependent
  • Almost clapping,
  • Trying so hard to form words, etc.

At six weeks: Today when we were touring the Roman theater in Cartagena Hannah was fussing but I was trying to talk to the other kids. All of a sudden she reached and grabbed my face with her hand and pushed it towards hers so that I would look at her. She tries to touch the keys when she sees us typing on a computer.

​*Gross motor (physical) skills, those which require whole body movement and which involve the large (core stabilizing) muscles of the body to perform everyday functions, such as standing and walking, running and jumping, and sitting upright at the table. They also includes eye-hand coordination skills such as ball skills (throwing, catching, kicking) as well as riding a bike or a scooter and swimming.

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